People may have different experiences when using compounded sublingual semaglutide. How someone feels or what they notice over time can vary based on many factors such as overall health, daily habits, and the treatment plan created by their healthcare provider. There is no specific or expected amount of weight change that applies to everyone.
If you have questions about what to expect or how you are responding to your medication, your healthcare provider can review your individual health needs and discuss your treatment plan with you.
Understanding Individual Experiences
Responses to medications can differ widely from person to person. Some individuals may notice changes in appetite or eating patterns, while others may not experience noticeable differences right away. Your provider may adjust your dose over time based on your tolerance, response, and overall treatment goals. Because compounded sublingual semaglutide has not been evaluated by the FDA, there is no established clinical data on expected outcomes or weight-related changes for this formulation.
If you are unsure whether your experience is typical for you or have questions about your progress, your healthcare provider is the best person to guide you.
What About Clinical Studies?
Clinical studies of FDA-approved injectable semaglutide apply only to those products and not to compounded formulations, including sublingual drops. Compounded medications may differ in formulation, absorption, dosing, and supporting evidence.
Your healthcare provider can help interpret which information is relevant for your personal treatment plan.
Factors That Can Influence Your Experience
Your provider may talk with you about elements such as:
- Nutrition and hydration
- Sleep habits
- Daily activity
- Your medical history
- Dose adjustments over time
These factors vary from person to person and may influence how you feel during treatment.

If you have concerns about whether your current plan is meeting your needs, your provider can help determine next steps.

Compounded medications are not FDA-approved. They are prepared by licensed compounding pharmacies under medical supervision and may differ in formulation, dosing, and supporting evidence from FDA-approved products.

This article is for general informational purposes only and does not provide medical advice, diagnosis or treatment for any specific person.