Is Sublingual Semaglutide Safe?

About Sublingual Semaglutide

Compounded sublingual semaglutide is prepared by licensed compounding pharmacies when prescribed by a healthcare provider. These formulations are not FDA-approved and may differ from FDA-approved semaglutide products in dosing, absorption, and available evidence.

Certain FDA-approved semaglutide medications have been studied in clinical trials for type 2 diabetes and weight management. Clinical studies of FDA-approved products apply only to those medications. Compounded formulations, including sublingual preparations, have not been evaluated by the FDA for safety or efficacy.

Your provider can help determine whether a compounded formulation is appropriate based on your health needs.

Possible Experiences and Considerations

People can have different experiences when starting any medication. Some individuals report digestive symptoms such as nausea, vomiting, or stomach discomfort when using semaglutide-based treatments. These experiences vary widely, and not everyone will have the same response.

Because compounded sublingual semaglutide has not been evaluated by the FDA, it is important to use it only under the guidance of a licensed healthcare provider. Your provider can review your medical history, monitor how you respond, and decide whether any adjustments are needed.

If you have questions about symptoms or how you are feeling during treatment, your healthcare provider is the best person to advise you.

Compounded medications are not FDA-approved. They are prepared by licensed compounding pharmacies under medical supervision and may differ in formulation, dosing, and supporting evidence from FDA-approved products.

This article is for general informational purposes only and does not provide medical advice, diagnosis or treatment for any specific person.

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