How do I take sublingual Tirzepatide?
Sublingual Tirzepatide should be taken exactly as directed on your prescription label and medication guide. Your label will list your prescribed volume, dosing frequency, and any instructions specific to your treatment plan.
Do not change your dose, take extra medication, or increase your dose unless instructed by your provider.
Before You Begin
Review your prescription label
Before preparing your medication, locate your prescription label and review:
- The prescribed volume, listed in mL
- Your dosing frequency
- Any special instructions from your provider or pharmacy
Your dosing schedule is prescribed specifically for you and your needs. If anything is unclear, contact us before taking your medication.
Managing doses during the first few months
During the first couple of months, especially at starter doses, it is normal to see little or no weight loss. These early doses help your body adjust before the medication is increased.
Most patients see gradual, steady progress after that. If you are concerned or not noticing changes, reach out and we can help review next steps with you.
Instructions
Step 1: Prepare your medication
- Wash your hands thoroughly.
- Shake the bottle well before each use.
- Use the provided dropper or dosing syringe to draw the prescribed amount of medication.
Step 2: Administer your medication
- Place the measured dose under your tongue.
- Hold it there for the amount of time listed in your instructions.
- Keep your mouth closed while holding the medication under your tongue.
- Avoid talking, swallowing, moving around, or lying down while the medication is being held in place.
- After the instructed time has passed, swallow any remaining liquid.
- Follow any additional instructions on your prescription label, including how long to wait before eating, drinking, or taking other medications.
Holding the dose under your tongue longer may improve absorption
When to take your medication
Take your medication at the same time according to your dosing schedule. Many patients prefer to take it in the morning before eating or at night before bed. Choose a time that works best for your schedule and allows you to hold the medication under your tongue without interruption.
If you miss a dose:
- Do not increase or double the amount to make up for the missed dose.
- Resume your schedule as normal with your next planned dose.
- Do not take multiple doses at one time.
Storage and handling
- Store medication at room temperature, tightly closed, away from direct sunlight and moisture.
- Do not refrigerate medication unless otherwise instructed by the pharmacy.
- Keep out of reach of children and pets.
- Do not share your medication.
Video Guide
Pamphlet
Need Help?
If you have questions about your prescription label, dosing schedule, or how to take your medication, contact Direct Meds support before taking your next dose.
Best results have generally been seen when taken as a daily morning dose, but medication can be taken once daily at whatever time is most convenient for you, so long as the main focus is a time that allows you to hold the medication under your tongue for as long as possible. As an example, some patients opt to take their medication at bedtime when things are more settled so they can hold the medication under their tongue for a longer period.
If you miss a dose, do not try to "make up" for the missed dose; just continue at the next scheduled dose. Do not take multiple doses at one time.
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