Certain substances and medications should not be combined with Direct Max 3-in-1 (Apomorphine, Sildenafil, & Tadalafil).
Do not use this medication if you take:
Nitrates for chest pain (such as nitroglycerin or isosorbide medications)
Recreational nitrates (such as amyl nitrate or “poppers”)
Riociguat (Adempas)
Use caution and consult your provider if you take:
Alpha-blockers
Certain antifungal medications
HIV protease inhibitors
Erythromycin
Trazodone
Other medications that affect blood pressure
Excess alcohol may increase the risk of dizziness or low blood pressure.


