What is the starter dose of sublingual Tirzepatide and how does it work?
When beginning treatment with compounded sublingual tirzepatide, people may start with a lower dose as determined by their healthcare provider. This approach allows your provider to monitor how you respond to treatment and make adjustments if needed.
Always read your prescription and follow the dosing instructions provided by your healthcare provider.
Your healthcare provider will determine the dose that is appropriate for your individual needs. The information below reflects a commonly used starter template, but your specific prescription may differ.
Typical 12-Week Starter Dose Schedule
(Always follow the dosing written on your prescription label.)
Weeks 1–4: 3 mg (0.3 mL) per day | Strength: 10 mg/mL (9 mL vial) |
Weeks 5–8: 4 mg (0.4 mL) per day | Strength: 10 mg/mL (12 mL vial) |
Weeks 9–12: 5 mg (0.5 mL) per day | Strength: 10 mg/mL (15 mL vial) |
Your provider may choose a different dosing schedule based on your medical history, treatment goals, and individual response. Always follow the instructions provided by your healthcare professional and the directions included with your prescription.

Compounded medications are not FDA-approved. They are prepared by licensed compounding pharmacies under medical supervision and may differ in formulation, dosing, and supporting evidence from FDA-approved products.

This article is for general informational purposes only and does not provide medical advice, diagnosis or treatment for any specific person.
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