About MOTS-C
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-type-c) is a potent mitochondrial-derived peptide (MDP). Often referred to as an "exercise mimetic," it functions as a metabolic regulator that mirrors many of the systemic benefits of physical activity.
- MOTS-C is a compounded peptide prescribed by a licensed provider
- It is primarily used to support metabolic health, helping the body burn fat more effectively and handle carbohydrates and blood sugar better over time
- It is administered as a subcutaneous injection and prescribed as a personalized, physician-supervised protocol
How It Works
MOTS-c works by flipping the body's AMPK switch, the cellular energy sensor. Once that switch is activated, the active ingredient facilitates three primary physiological outcomes:
- Glucose translocation (fuel intake): MOTS-c prompts GLUT4 transporters to move to the surface of muscle cells, allowing muscle to take up sugar from the blood without needing high levels of insulin. This is why it is often called an "exercise mimetic," it mimics the process that happens when you lift weights or run.
- Fat oxidation (burning the backlog): It signals the body to break down stored fats for energy and inhibits the creation of new fat, so stored body fat is used for fuel rather than added to.
- Mitochondrial biogenesis (upgrading the hardware): It signals the cell to create new mitochondria, making your existing energy system work harder and more efficiently.
What to Expect
MOTS-C is designed to help the tiny energy factories inside your cells (your mitochondria) run more efficiently for steadier, all-day energy. It trains your body to burn fat more effectively, especially when paired with movement, makes workouts feel easier with faster recovery, and supports the metabolic resilience that quietly slips away after 40.
Safety Considerations
MOTS-C is not for use in patients who have cancer, a history of cancer, or who are pregnant or breastfeeding. A medical assessment is required before MOTS-C is prescribed.