What are the potential side effects of Estradiol Vaginal Cream?

What are the potential side effects of Estradiol Vaginal Cream?

Common/mild (may resolve as your body adjusts): Headache, dizziness, stomach upset, bloating, weight changes, change in sex drive, breast tenderness, mood changes, and menstrual irregularities.

Serious (seek in-person medical attention): Chest pain, one-sided weakness, slurred speech, sudden vision changes, swelling of hands or feet, severe mood changes (depression or memory loss), heavy prolonged vaginal bleeding, breast lumps, or signs of liver problems.
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