Refrigeration is best practice
Always store your compounded Semaglutide in the refrigerator (36°–46°F) whenever possible.
Factory-Sealed Medication
If your vial arrives with the seal still intact, it can remain at room temperature (68°–80°F) for up to 21 days, including time spent in shipping or brief periods outside the refrigerator.
Opened or Pierced Medication
Once the vial’s seal has been opened or pierced, it must be placed in the refrigerator right away to maintain proper storage conditions.
Melted Ice Pack
It is common for ice packs to melt during transit. If the vial is sealed, simply refrigerate your medication as soon as you receive the package.
Key Point: Room-temperature stability is a temporary allowance, not a replacement for proper refrigeration.
This article is for general informational purposes only and does not provide medical advice, diagnosis or treatment for any specific person.

Compounded medications are not FDA-approved. They are prepared by licensed compounding pharmacies under medical supervision and may differ in formulation, dosing, and supporting evidence from FDA-approved products.