Response times and duration can vary from person to person.
Direct Max 3-in-1 (Apomorphine, Sildenafil, & Tadalafil) contains active ingredients that are absorbed sublingually (under the tongue). Some individuals may begin to notice effects within approximately 15–30 minutes. However, timing can differ based on metabolism, overall health, food intake, and other medications.
The duration of effects may also vary. One of the ingredients (sildenafil) is typically active for several hours, while another ingredient (tadalafil) may remain active in the body longer. Individual response depends on many factors.
Your healthcare provider can help set expectations based on your health profile. This medication does not cause automatic erections and requires sexual stimulation to be effective.

