Yes. Keep microdosing semaglutide refrigerated between 35°F and 46°F (2°C to 8°C), including after the vial has been opened or punctured.
Brief temperature excursions between 35°F and 113°F (2°C to 45°C) for up to 120 hours (5 days) are acceptable. Return the medication to refrigerated storage as soon as possible.
Protect the vial from excessive heat, direct sunlight, and freezing. Always follow the pharmacy’s storage instructions and the Beyond-Use Date printed on your prescription label.


