At this time, Direct Meds does not offer a B12-free formulation of compounded injectable tirzepatide. All tirzepatide injections dispensed through Direct Meds are compounded with Vitamin B12 (cyanocobalamin) as part of the standard formulation used by our compounding pharmacy. If you have questions about this formulation or whether it is appropriate for your health needs, your healthcare provider can review your medical history and discuss any alternative treatment options that may be available outside of Direct Meds.
Why Is B12 Included?
Compounded tirzepatide may contain additional ingredients based on the formulation practices of the compounding pharmacy and the prescribing provider’s instructions. Vitamin B12 is one of the ingredients included in the compounded preparation offered by Direct Meds. The inclusion of B12 does not replace tirzepatide, change its intended use, or indicate any specific health benefit on its own. If you have questions about your prescribed formulation, your provider or pharmacy team can explain how it was determined.
Questions About Your Prescription?
If you are unsure whether the formulation containing B12 is appropriate for you, speak with your healthcare provider. They can help determine whether tirzepatide is suitable for your health needs and discuss any alternatives if needed.
Compounded versions of tirzepatide are not FDA-approved. The FDA has not evaluated compounded tirzepatide for safety, effectiveness, or quality. Compounded medications may differ in formulation, strength, or supporting evidence from FDA-approved products.

This article is for general informational purposes only and does not provide medical advice, diagnosis or treatment for any specific person.