Yes.

Microdosing semaglutide should be kept refrigerated between 35°F and 46°F (2°C to 8°C) whenever possible.

Cold-storage travel options, including insulated medication bags and portable medication coolers, are available for purchase online or through many local pharmacies.

Brief temperature excursions outside the normal refrigerated range are acceptable. The medication may tolerate temperatures between 32°F and 113°F (0°C to 45°C) for limited periods, with testing showing approximately 98% potency after excursions of up to 120 hours.

If the medication appears to have frozen, do not use it. Contact Direct Meds for assistance with replacement.

When traveling:

• Keep the medication in its original labeled packaging.

• Keep it with you in your carry-on luggage rather than checked baggage when flying.

• Use a cold-storage option when possible.

• Avoid leaving the medication in a hot or freezing vehicle.
  

Contact clinicalcare@directmeds.com for assistance before your trip.

Compounded medications are not FDA-approved. They are prepared by licensed compounding pharmacies under medical supervision and may differ in formulation, dosing, and supporting evidence from FDA-approved products.

This article is for general informational purposes only and does not provide medical advice, diagnosis or treatment for any specific person. 

If you ever have questions about medication stability, you can contact our support team for additional details.